A model of haematopoiesis that links self-organisation with symmetric and asymmetric cell division is presented in this paper. It is assumed that all cell divisions are completely random events, and that the daughter cells resulting from symmetric and asymmetric stem cell divisions are, in general, phenotypically identical, and still, the haematopoietic system has the flexibility to self-renew, ...

In this thesis, we explore the stability and the breakdown of stability of biological systems. The main examples are the blood system and invasion of cancer. However, the models presented in the thesis apply to several other examples. Biological systems are characterised by both competition and cooperation. Cooperation is based on an unsolvable dilemma: Even though mutual cooperation leads to ...